Gute Nachrichten für alle die an Reizdarm Syndrom, häufigen Bauchschmerzen oder Angstzuständen leiden!
In der bisher größten kontrollierten Studie (doppelblind randomisiert - der Goldstandard für die medizinische Forschung) von Lebendbakterienergänzungen bei Patienten mit IBS-Diarrhoe-Typ, die jemals durchgeführt wurde, wurden dramatische Verbesserungen der Symptome berichtet.
- 69% Abnahme der Bauchschmerzen
- 86% Rückgang der mittelschweren bis schweren Symptome
- 34% gaben an, dass ihre Symptome nach 16 Wochen vollständig verschwunden sind
Die 14 Stämme lebender Bakterien in Bio-Kult Original haben gezeigt, dass sie nicht nur Bauchschmerzen bei IBS-Patienten dramatisch verbessern, sondern auch Angstzustände reduzieren.
Lesen Sie im folgenden die Zusammenfassung unserer Kollegen von Bio-Kult in englischer Sprache. Die kompletten Studienresultate können hier eingesehen werden.
Bio-Kult Original sind für die Schweiz online erhältlich in unserem Shop hier, sowie direkt bei www.bio-kult.ch
The 14 strains of “gut-friendly” bacteria in Bio-Kult have been shown to not only dramatically improve abdominal pain in IBS patients but reduce anxiety too. In the largest-ever double-blind randomised controlled trial (the gold standard for medical research) of live bacteria supplements in IBS-diarrhoea type patients ever-conducted, dramatic improvements in symptoms have been reported.
- In the study of 360 patients who had IBS with diarrhoea as their predominant symptom (IBS-D); those patients who took the probiotic supplement Bio-Kult® reported a 69 per cent decrease in abdominal pain, compared to 47 per cent in a group who took a placebo.
- The four-month study conducted by the University of Bangabandhu Sheikh Mujib Medical University in Dhaka, Bangladesh also found the number of patients who rated their symptoms as moderate to severe at the beginning of the study was reduced by 86 per cent in the Bio-Kult® group, compared to only 52 per cent in those who took a placebo.
Significantly though, as well as relieving IBS-D symptoms, Bio-Kult® was also shown to markedly improve all aspects of Quality of Life (QoL) evaluated using as 34 point IBS-QoL questionnaire. These included psychological issues such as anxiety about health, depression, lack of enjoyment of life, and feelings of having to avoid stressful situations.
- A total of 33.7 per cent in the Bio-Kult® group said all their symptoms had disappeared at the end of the 16 weeks compared to just 12.8 per cent in the placebo group.
Significantly though, as well as relieving IBS-D symptoms, Bio-Kult® was also shown to markedly improve all aspects of Quality of Life (QoL) evaluated using as 34 point IBS-QoL questionnaire. These included psychological issues such as anxiety about health, depression, lack of enjoyment of life, and feelings of having to avoid stressful situations.
Leading experts say the findings are a significant breakthrough in understanding the role bacteria play in not only physical gut symptoms, but also psychological symptoms of IBS too.
Dr Philip Burnet, Associate Professor at Oxford University, a leading UK expert on the gut microbiome/ brain axis, says that although several symptoms within the IBS-QoL survey in the study were significantly improved after taking probiotic supplements the reduction in dysphoria (unease or generalised dissatisfaction), and health worries were particularly noteworthy.
'The influence of gut bacteria on the brain is a topical area of research in neuroscience and the microbiome-gut-brain-axis is considered a potential therapeutic pathway for brain disorders,' says Dr Burnet.' Using probiotics that influence brain function, or the so called "psychobiotics", may in the future help alleviate conditions such as depression and anxiety. 'Indeed, there is a strong link between depression and IBS, and some researchers have suggested that mood disorders themselves may arise from dysbiosis (a microbial imbalance within the body such as within the gut).'
Dr Burnet says another recent study by the University of Corki has demonstrated that a single-strain probiotic, B.Longum, reduced depression scores in 22 IBS patients.
'Importantly, the Bio-Kult® formulation not only contains B.Longum but also several other probiotic strains that have been reported to have psychotropic effects in both mouse models of anxiety and depressed mood, and in preliminary human studies,' says Dr Burnet.
'Therefore, the current trial not only demonstrated the therapeutic effects of Bio-Kult® in IBS, but has also alluded to its possible anxiety-lowering effects by reducing the incidence of health worries, social reactions and body image issues in participants. '
Professor Glenn Gibson, professor of food microbiology at the University of Reading said few effective therapies for IBS exist and it was extremely encouraging to see the positive results of the Bio-Kult® study.
'The mechanism of action is likely to be positive influences of the probiotic on gut microbiology - known to be both positive and negative for health. This user-friendly and safe approach offers new hope for millions of IBS patients worldwide,' he says.
Study leader Professor Shamsuddin Ishaque said: 'Over a period of 16 weeks Bio-Kult® produced statistically significant improvements in all key symptoms of IBS-D compare to placebo; including the severity and frequency of abdominal pain. The magnitude of these changes with Bio-Kult® were also very impressive’.
“IBS is a significant problem that decreases quality of life and places an enormous economic burden on healthcare systems globally. In the UK alone as many as 8 million of us suffer with this chronic condition. A safe and convenient IBS treatment that is capable of reducing pain by nearly 70%, not to mention completely resolving symptoms in more than a third of patients, demonstrates a profound benefit and holds great promise for this major medical concern”. Says Dr Ashton Harper, Head of Medical Affairs, Protexin Healthcare.
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